Guillaume Combet graduated with a Premier Prix (First Prize) in Violin and Chamber Music from the Conservatoire National Supérieur de Musique de Paris where he studied with Gérard Poulet and Sylvie Gazeau, and received his Advanced Certificate in Violin Performance from The Juilliard School where he studied with Joel Smirnoff, Robert Mann and William Lincer. 

Guillaume was concertmaster of the Chicago Civic Orchestra under Barenboim and Boulez, soloist and assistant concertmaster of the Chicago String Ensemble, soloist with the Orchestre Symphonique de Tours, and toured internationally with Les Virtuoses de France. He has performed with numerous orchestras in Paris, Chicago and Philadelphia—Orchestra de l’Opéra de Paris Bastille, Lyric Opera of Chicago, Chicago Symphony Orchestra, Fulcrum Point New Music Project, Network for New Music, Opera Philadelphia, Philly Pops, and Pennsylvania Ballet. As a sought-after chamber musician, he has performed throughout the country including at the Luckman Fine Arts Complex in Los Angeles, the Chicago Cultural Center on the WFMT Dame Myra Hess Concert Series, the University of Chicago, the University of Delaware, Temple University, and the Philadelphia Ethical Society.  In addition to chamber music and orchestral playing, Guillaume has also devoted his life to teaching violin and chamber music, and his students have won major scholarships, competitions and awards.  He currently teaches at the University of Pennsylvania and Temple University Music Preparatory Division, and has taught at the Merit School of Music in Chicago and the University of Illinois at Chicago.  Beginning in the Fall term of 2019 Guillaume has been named Associate Professor of Violin in the School of Music of the University of Delaware in Newark, Delaware.